Transforming the future of

We provide scientists with advanced epigenetic testing services and bioinformatic tools that support groundbreaking research.

Research

Collaborations

Physicians’ Health Study
  • Epigenetic data on 11,340 physicians
  • 30 years follow-up
  • 2,000+ mortality events and other major diseases
VITAL Study
  • Epigenetic data in 800 men and women
  • Clinical trial on vitamin D3 and omega-3 fatty acids (fish oil) supplementation
  • Focus on cancer, heart disease, and stroke
Cocoa Flavanols and Multivitamins Trial
  • Epigenetic data in 1,200 men and women
  • Clinical trial on multivitamins and cocoa flavanol supplementation
  • Focus on cancer, heart disease, and stroke
FOXO USA Study
  • Epigenetic data in blood and saliva of ~5,000 men and women
  • Nation-wide study collecting blood, urine, saliva, and medical records.
  • Focus on tobacco use, alcohol use, diabetes, obesity, hypertension, and dyslipidemia
Industry Pilot Studies
  • Company-specific examinations of epigenetic tests in life insurance application processes
  • Provides data for companies to tailor epigenetic testing into their unique workflows
Substance Abuse Study
  • Epigenetic data in over 400 men and women
  • Focus on cocaine and opiate abuse
epigenetic testing services

Move your research forward

We provide end-to-end, cost-effective DNA methylation testing and analysis in a high throughput, CLIA-certified laboratory for mice and humans.

Our proprietary IP covers a wide swath of technology in the use of epigenetic biomarkers associated with longevity risk classification, probe selection, advanced supervised machine learning, and AI.

Infinium human methylation array

Our first-of-its-kind Human Methylation Array enables researchers to seamlessly process human samples and examine thousands of CpGs using state-of-the-art bioinformatics.

Infinium mouse methylation array

Our Mouse Methylation array was developed with Van Andel Institute and Illumina to support biological research in precision-based diagnostics, therapeutic medicine, and longevity.

Open source. Common goal.

We believe in sharing tools and resources that support the research community and lead to groundbreaking epigenetic discoveries. Our open source bioinformatic software packages simplify and automate the labor-intensive preprocessing, quality control, and analyses commonly involved in the study of complex DNA methylation data.

Automated

Automates analysis of epigenetic data from Illumina arrays that measure DNA modifications that are altered in response to human behavior and biological processes

Written in Python

These open source software packages can run natively in command line, Jupyter notebooks, or automation scripts

Pre-processing and quality control

Improves user experience for researchers by automating previously laborious steps in epigenetic data pre-processing and quality control

Bioinformatics software methylsuite

Methylprep

Methylprep is part of a methylsuite of Python packages that provide functions to process and analyze DNA methylation data from Illumina arrays (27, 450k & EPIC/850k supported) and download/process public data sets from GEO or ArrayExpress.

Methylcheck

Methylcheck works in conjunction with Methylprep and contains high-level APIs for filtering processed data from local files that have been downloaded from the NIH GEO database or processed as a set of idat files.

Methylize

Run linear or logistic regression on all probes to identify points of interest in the methylome where DNA is differentially modified. These regression results can then be used to create volcano plots and manhattan plots.

What can FOXO do for you?